Purification and biochemical characterization of a novel protein—tongue cancer chemotherapy resistance-associated protein1 (TCRP1)

B Peng, S Yi, Y Gu, G Zheng, Z He - Protein Expression and Purification, 2012 - Elsevier
Multidrug resistance is a major obstacle to successful treatment of oral squamous cell
carcinoma (OSCC). Lately, we found a novel human gene named tongue cancer
chemotherapy resistance-associated protein1 (TCRP1) in the tongue cancer multi-drug
resistance cell line (Tca8113/PYM) established by us. In this study, we focus on recombinant
expression, purification, and biochemical characterization of TCRP1. After molecular cloning
and purification of the gene encoding the 24-kDa protein, a mouse polyclonal antibody …