Cancer is a daunting global problem confronting the world's population. The most frequent
therapeutic approaches include surgery, chemotherapy, radiotherapy, and more recently
immunotherapy. In the case of chemotherapy, patients ultimately develop resistance to both
single and multiple chemotherapeutic agents, which can culminate in metastatic disease
which is a major cause of patient death from solid tumors. Chemoresistance, a primary
cause of treatment failure, is attributed to multiple factors including decreased drug …