[HTML][HTML] Oocyte environment: follicular fluid and cumulus cells are critical for oocyte health
DA Dumesic, DR Meldrum, MG Katz-Jaffe, RL Krisher… - Fertility and sterility, 2015 - Elsevier
Bidirectional somatic cell–oocyte signaling is essential to create a changing intrafollicular
microenvironment that controls primordial follicle growth into a cohort of growing follicles,
from which one antral follicle is selected to ovulate a healthy oocyte. Such intercellular
communications allow the oocyte to determine its own fate by influencing the intrafollicular
microenvironment, which in turn provides the necessary cellular functions for oocyte
developmental competence, which is defined as the ability of the oocyte to complete meiosis …
microenvironment that controls primordial follicle growth into a cohort of growing follicles,
from which one antral follicle is selected to ovulate a healthy oocyte. Such intercellular
communications allow the oocyte to determine its own fate by influencing the intrafollicular
microenvironment, which in turn provides the necessary cellular functions for oocyte
developmental competence, which is defined as the ability of the oocyte to complete meiosis …