[HTML][HTML] Obesity and female infertility: potential mediators of obesity's impact
DE Broughton, KH Moley - Fertility and sterility, 2017 - Elsevier
The worldwide upward trend in obesity has been dramatic, now affecting more than 20% of
American women of reproductive age. Obesity is associated with many adverse maternal
and fetal effects prenatally, but it also exerts a negative influence on female fertility. Obese
women are more likely to have ovulatory dysfunction due to dysregulation of the
hypothalamic-pituitary-ovarian axis. Women with polycystic ovarian syndrome who are also
obese demonstrate a more severe metabolic and reproductive phenotype. Obese women …
American women of reproductive age. Obesity is associated with many adverse maternal
and fetal effects prenatally, but it also exerts a negative influence on female fertility. Obese
women are more likely to have ovulatory dysfunction due to dysregulation of the
hypothalamic-pituitary-ovarian axis. Women with polycystic ovarian syndrome who are also
obese demonstrate a more severe metabolic and reproductive phenotype. Obese women …