Regulation of gut hormone secretion. Studies using isolated perfused intestines
B Svendsen, JJ Holst - Peptides, 2016 - Elsevier
The incretin hormones glucagon-like peptide 1 (GLP-1) and glucose-dependent
insulinotropic polypeptide (GIP) are secreted from enteroendocrine cells in the intestine
along with other gut hormones (PYY, CCK and neurotensin) shown to affect metabolism
and/or appetite. The secretion of many gut hormones is highly increased after gastric bypass
operations, which have turned out to be an effective therapy of not only obesity but also type
2 diabetes. These effects are likely to be due, at least in part, to increases in the secretion of …
insulinotropic polypeptide (GIP) are secreted from enteroendocrine cells in the intestine
along with other gut hormones (PYY, CCK and neurotensin) shown to affect metabolism
and/or appetite. The secretion of many gut hormones is highly increased after gastric bypass
operations, which have turned out to be an effective therapy of not only obesity but also type
2 diabetes. These effects are likely to be due, at least in part, to increases in the secretion of …
