Mitochondrial DNA variants and pulmonary function in older persons

CAV Fragoso, TM Manini, JA Kairalla, TW Buford… - Experimental …, 2019 - Elsevier
Background We provide the first examination of mitochondrial DNA (mtDNA) variants and
pulmonary function in older persons. Methods Cross-sectional associations between mtDNA
variants and pulmonary function were evaluated as a combined p-values meta-analysis,
using data from two independent cohorts of older persons. The latter included white and
black participants, aged≥ 70 years, from the Lifestyle Interventions and Independence for
Elders study (LIFE)(N= 1247) and the Health, Aging and Body Composition study (Health …