Interactions between the gonadal steroids and the immune system

CJ Grossman - Science, 1985 - science.org
CJ Grossman
Science, 1985science.org
The immune system is regulated by the gonadal steroids estrogen, androgen, and
progesterone, but the circulating levels of these steroids can also be affected by immune
system function. Such interactions appear to be mediated through the hypothalamic-pituitary-
gonadal-thymic axis and depend on pituitary luteinizing hormone released by thymic factors
under the control of the gonadal steroids.
The immune system is regulated by the gonadal steroids estrogen, androgen, and progesterone, but the circulating levels of these steroids can also be affected by immune system function. Such interactions appear to be mediated through the hypothalamic-pituitary-gonadal-thymic axis and depend on pituitary luteinizing hormone released by thymic factors under the control of the gonadal steroids.
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