Role of platelet-derived growth factor in mesangium development and vasculopathies: lessons from platelet-derived growth factor and platelet-derived growth factor …
C Betsholtz, P Lindblom, M Bjarnegard… - Current opinion in …, 2004 - journals.lww.com
C Betsholtz, P Lindblom, M Bjarnegard, M Enge, H Gerhardt, P Lindahl
Current opinion in nephrology and hypertension, 2004•journals.lww.comThese microvascular abnormalities and their consequences bear a resemblance to diabetic
microangiopathy and nephropathy. The platelet-derived growth factor-B and platelet-derived
growth factor β-receptor mutant mouse models, therefore, might serve as valuable tools in
the dissection of some of the pathogenic events in diabetic microangiopathy.
microangiopathy and nephropathy. The platelet-derived growth factor-B and platelet-derived
growth factor β-receptor mutant mouse models, therefore, might serve as valuable tools in
the dissection of some of the pathogenic events in diabetic microangiopathy.
Summary
These microvascular abnormalities and their consequences bear a resemblance to diabetic microangiopathy and nephropathy. The platelet-derived growth factor-B and platelet-derived growth factor β-receptor mutant mouse models, therefore, might serve as valuable tools in the dissection of some of the pathogenic events in diabetic microangiopathy.
Lippincott Williams & Wilkins