Ginger (Zingiber officinale) and rheumatic disorders
KC Srivastava, T Mustafa - Medical hypotheses, 1989 - Elsevier
Oxygenation of arachidonic acid is increased in inflamed tissues. In this condition products
of two enzymic pathways—the cyclooxygenase and the 5-lipoxygenase producing
respectively prostaglandins and leukotrienes—are elevated. Of the cyclooxygenase
products, PGE 2 and of the lipoxygenase products, LTB 4 are the strongest candidates for
mediating inflammation. Non-steroidal anti-inflammatory drugs which inhibit the
cyclooxygenase, and corticosteroids are used to treat such disorders. Both types of drugs …
of two enzymic pathways—the cyclooxygenase and the 5-lipoxygenase producing
respectively prostaglandins and leukotrienes—are elevated. Of the cyclooxygenase
products, PGE 2 and of the lipoxygenase products, LTB 4 are the strongest candidates for
mediating inflammation. Non-steroidal anti-inflammatory drugs which inhibit the
cyclooxygenase, and corticosteroids are used to treat such disorders. Both types of drugs …
