Mice are prime targets of experimental gene modification and have become object of an
increasing number of biologic studies in renal physiology, development, and molecular
biology. Phenotypic changes in response to gene modification require detailed information
on normal structure. However, detailed analyses of normal mouse kidney structure and
organization are lacking. This study describes the 3D organization and ultrastructural,
segmental variation of the mouse kidney proximal tubule. A total of 160 proximal tubules in …