[HTML][HTML] Unraveling the complexities of the HDL lipidome1
A Kontush, M Lhomme, MJ Chapman - Journal of lipid research, 2013 - ASBMB
Plasma high density lipoproteins (HDL) are small, dense, protein-rich particles compared
with other lipoprotein classes; roughly half of total HDL mass is accounted for by lipid
components. Phospholipids predominate in the HDL lipidome, accounting for 40–60% of
total lipid, with lesser proportions of cholesteryl esters (30–40%), triglycerides (5–12%), and
free cholesterol (5–10%). Lipidomic approaches have provided initial insights into the HDL
lipidome with identification of over 200 individual molecular lipids species in normolipidemic …
with other lipoprotein classes; roughly half of total HDL mass is accounted for by lipid
components. Phospholipids predominate in the HDL lipidome, accounting for 40–60% of
total lipid, with lesser proportions of cholesteryl esters (30–40%), triglycerides (5–12%), and
free cholesterol (5–10%). Lipidomic approaches have provided initial insights into the HDL
lipidome with identification of over 200 individual molecular lipids species in normolipidemic …