Cytokine levels in critically ill patients with COVID-19 and other conditions

M Kox, NJB Waalders, EJ Kooistra, J Gerretsen… - Jama, 2020 - jamanetwork.com
Methods| All patients in this study were admitted to the intensive care unit (ICU) of Radboud
University Medical Center. Plasma concentrations of the proinflammatory cytokines tumor
necrosis factor (TNF), IL-6, and IL-8 were determined in consecutive mechanically ventilated
patients with COVID-19 with ARDS (partial pressure of oxygen/fraction of inspired oxygen
ratio< 300; sampled within 48 hours after ICU admission), bacterial septic shock with or
without ARDS (sampled within 24 hours after septic shock diagnosis), outof-hospital cardiac …