Diagnostic performance of RO948 F 18 tau positron emission tomography in the differentiation of Alzheimer disease from other neurodegenerative disorders

A Leuzy, R Smith, R Ossenkoppele, A Santillo… - JAMA …, 2020 - jamanetwork.com
Importance The diagnostic performance of second-generation tau positron emission
tomographic (PET) tracers is not yet known. Objective To examine the novel tau PET tracer
RO948 F 18 ([18 F] RO948) performance in discriminating Alzheimer disease (AD) from non-
AD neurodegenerative disorders. Design, Setting, and Participants In this diagnostic study,
613 participants in the Swedish BioFINDER-2 study were consecutively enrolled in a
prospective cross-sectional study from September 4, 2017, to August 28, 2019. Participants …