Discriminative accuracy of FEV1: FVC thresholds for COPD-related hospitalization and mortality

SP Bhatt, PP Balte, JE Schwartz, PA Cassano… - Jama, 2019 - jamanetwork.com
Importance According to numerous current guidelines, the diagnosis of chronic obstructive
pulmonary disease (COPD) requires a ratio of the forced expiratory volume in the first
second to the forced vital capacity (FEV 1: FVC) of less than 0.70, yet this fixed threshold is
based on expert opinion and remains controversial. Objective To determine the
discriminative accuracy of various FEV 1: FVC fixed thresholds for predicting COPD-related
hospitalization and mortality. Design, Setting, and Participants The National Heart, Lung …