Preeclampsia remains a leading cause of maternal and fetal morbidity and mortality and has
an unknown etiology. The limited progress made regarding new treatments to reduce the
incidence and severity of preeclampsia has been attributed to the difficulties faced in the
development of suitable animal models for the mechanistic research of this disease. In
addition, animal models need hypotheses on which to be based and the slow development
of testable hypotheses has also contributed to this poor progress. The past decade has seen …