Interleukin-8 serum levels in patients with benign prostatic hyperplasia and prostate cancer

RW Veltri, MC Miller, G Zhao, A Ng, GM Marley… - Urology, 1999 - Elsevier
Objectives. Using arbitrarily primed polymerase chain reaction (AP-PCR) ribonucleic acid
(RNA) fingerprinting, we discovered a messenger RNA (mRNA) that encoded the cytokine
interleukin-8 (IL-8) that was up-regulated in the peripheral blood leukocytes (PBLs) of
patients with metastatic prostate cancer (CaP) compared with similar cells from healthy
individuals. We compared the total prostate-specific antigen (PSA) levels, the free/total (f/t)
PSA ratios, and the immunoreactive IL-8 serum concentrations in patients with either biopsy …