[HTML][HTML] Uric acid induces hepatic steatosis by generation of mitochondrial oxidative stress: potential role in fructose-dependent and-independent fatty liver
MA Lanaspa, LG Sanchez-Lozada, YJ Choi… - Journal of Biological …, 2012 - ASBMB
Metabolic syndrome represents a collection of abnormalities that includes fatty liver, and it
currently affects one-third of the United States population and has become a major health
concern worldwide. Fructose intake, primarily from added sugars in soft drinks, can induce
fatty liver in animals and is epidemiologically associated with nonalcoholic fatty liver disease
in humans. Fructose is considered lipogenic due to its ability to generate triglycerides as a
direct consequence of the metabolism of the fructose molecule. Here, we show that fructose …
currently affects one-third of the United States population and has become a major health
concern worldwide. Fructose intake, primarily from added sugars in soft drinks, can induce
fatty liver in animals and is epidemiologically associated with nonalcoholic fatty liver disease
in humans. Fructose is considered lipogenic due to its ability to generate triglycerides as a
direct consequence of the metabolism of the fructose molecule. Here, we show that fructose …