Pulmonary complications of sickle cell disease

MT Gladwin, E Vichinsky - New England journal of medicine, 2008 - Mass Medical Soc
MT Gladwin, E Vichinsky
New England journal of medicine, 2008Mass Medical Soc
This review presents evidence for two overlapping yet distinctive clinical types of sickle cell
disease. The basis of one is the vaso-occlusive crisis; the other is the consequence of
intravascular hemolysis. The authors focus on the acute vaso-occlusive crisis, the acute
chest syndrome, and pulmonary hypertension, all common complications of sickle cell
disease.
This review presents evidence for two overlapping yet distinctive clinical types of sickle cell disease. The basis of one is the vaso-occlusive crisis; the other is the consequence of intravascular hemolysis. The authors focus on the acute vaso-occlusive crisis, the acute chest syndrome, and pulmonary hypertension, all common complications of sickle cell disease.
The New England Journal Of Medicine