Tissue injury and the inflammatory response to pediatric cardiac surgery with cardiopulmonary bypass: a descriptive study

MS Chew, I Brandslund, V Brix-Christensen… - The Journal of the …, 2001 - pubs.asahq.org
Background There are few detailed descriptions of the inflammatory response to cardiac
surgery with cardiopulmonary bypass (CPB) in children beyond 24 h postoperatively. This is
especially true for the antiinflammatory cytokines and the extent of tissue injury. The aim of
the current study was to describe the inflammatory and injury responses in uncomplicated
pediatric cardiac surgery with CPB, where methylprednisolone and modified ultrafiltration
(MUF) were used. Methods Blood samples were collected up to 48 h postoperatively …