Chronic inflammation in psoriasis and obesity: implications for therapy
EA Hamminga, AJ van der Lely, HAM Neumann… - Medical hypotheses, 2006 - Elsevier
A recent study has shown an indisputable relationship between psoriasis and obesity.
Obesity leads to a higher risk in developing psoriasis and a poorer long-term clinical
outcome of psoriasis. Furthermore, loosing weight may improve the psoriasis. A network of
pro-inflammatory cytokines (especially tumour necrosis factor alpha (TNF-α)) is believed to
play an important role in the pathophysiology of both obesity and psoriasis. The chronic low-
level inflammation-as seen in obesity–may contribute to the extent of psoriatic lesions in …
Obesity leads to a higher risk in developing psoriasis and a poorer long-term clinical
outcome of psoriasis. Furthermore, loosing weight may improve the psoriasis. A network of
pro-inflammatory cytokines (especially tumour necrosis factor alpha (TNF-α)) is believed to
play an important role in the pathophysiology of both obesity and psoriasis. The chronic low-
level inflammation-as seen in obesity–may contribute to the extent of psoriatic lesions in …