[HTML][HTML] Distribution of the H+/peptide transporter PepT1 in human intestine: up-regulated expression in the colonic mucosa of patients with short-bowel syndrome
TR Ziegler, C Fernández-Estívariz, LH Gu… - The American journal of …, 2002 - Elsevier
Background: Intestinal adaptation after massive bowel resection in animal models is
characterized by increased gut-mucosal growth and expression of nutrient transporters. Few
data about these indexes exist in humans with short-bowel syndrome (SBS). Objective: The
objective was to compare small-bowel and colonic mucosal growth and expression of the
peptide transporter PepT1 in adults with or without SBS. Design: Mucosal biopsy specimens
were obtained from the small bowel and colon of 33 control subjects with intact intestine and …
characterized by increased gut-mucosal growth and expression of nutrient transporters. Few
data about these indexes exist in humans with short-bowel syndrome (SBS). Objective: The
objective was to compare small-bowel and colonic mucosal growth and expression of the
peptide transporter PepT1 in adults with or without SBS. Design: Mucosal biopsy specimens
were obtained from the small bowel and colon of 33 control subjects with intact intestine and …