[HTML][HTML] Role of receptor for hyaluronic acid-mediated motility (RHAMM) in low molecular weight hyaluronan (LMWHA)-mediated fibrosarcoma cell adhesion
K Kouvidi, A Berdiaki, D Nikitovic, P Katonis… - Journal of Biological …, 2011 - ASBMB
Hyaluronan (HA) modulates key cancer cell functions through interaction with its CD44 and
receptor for hyaluronic acid-mediated motility (RHAMM) receptors. HA was recently found to
regulate the migration of fibrosarcoma cells in a manner specifically dependent on its size.
Here, we investigated the effect of HA/RHAMM signaling on the ability of HT1080
fibrosarcoma cells to adhere onto fibronectin. Low molecular weight HA (LMWHA)
significantly increased (p≤ 0.01) the adhesion capacity of HT1080 cells, which high …
receptor for hyaluronic acid-mediated motility (RHAMM) receptors. HA was recently found to
regulate the migration of fibrosarcoma cells in a manner specifically dependent on its size.
Here, we investigated the effect of HA/RHAMM signaling on the ability of HT1080
fibrosarcoma cells to adhere onto fibronectin. Low molecular weight HA (LMWHA)
significantly increased (p≤ 0.01) the adhesion capacity of HT1080 cells, which high …