[HTML][HTML] Circulating innate lymphoid cells are unchanged in response to DAC HYP therapy
GO Gillard, SA Saenz, DJ Huss, JD Fontenot - Journal of neuroimmunology, 2016 - Elsevier
Innate lymphoid cells (ILCs) play an important role in immunity, inflammation, and tissue
remodeling and their dysregulation is implicated in autoimmune and inflammatory disorders.
We analyzed the impact of daclizumab, a humanized monoclonal anti-CD25 antibody, on
circulating natural killer (NK) cells and ILCs in a cohort of multiple sclerosis patients. An
increase in CD56 bright NK cells and CD56 hi CD16 intermediate transitional NK cells was
observed. No significant change in total ILCs or major ILC subpopulations was observed …
remodeling and their dysregulation is implicated in autoimmune and inflammatory disorders.
We analyzed the impact of daclizumab, a humanized monoclonal anti-CD25 antibody, on
circulating natural killer (NK) cells and ILCs in a cohort of multiple sclerosis patients. An
increase in CD56 bright NK cells and CD56 hi CD16 intermediate transitional NK cells was
observed. No significant change in total ILCs or major ILC subpopulations was observed …