Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level
ContextSerum hepatitis B virus (HBV) DNA level is a marker of viral replication and efficacy
of antiviral treatment in individuals with chronic hepatitis B. ObjectiveTo evaluate the
relationship between serum HBV DNA level and risk of hepatocellular carcinoma. Design,
Setting, and ParticipantsProspective cohort study of 3653 participants (aged 30-65 years),
who were seropositive for the hepatitis B surface antigen and seronegative for antibodies
against the hepatitis C virus, recruited to a community-based cancer screening program in …
of antiviral treatment in individuals with chronic hepatitis B. ObjectiveTo evaluate the
relationship between serum HBV DNA level and risk of hepatocellular carcinoma. Design,
Setting, and ParticipantsProspective cohort study of 3653 participants (aged 30-65 years),
who were seropositive for the hepatitis B surface antigen and seronegative for antibodies
against the hepatitis C virus, recruited to a community-based cancer screening program in …