Microbial infections, localized as well as systemic, are known to cause transitive or
permanent male infertility. However, the mechanisms of infection-induced infertility are
largely unknown. Earlier reports showed that steroidogenesis and spermatogenesis are
affected during bacterial lipopolysaccharide (LPS)-induced acute inflammation. The present
study used an LPS rat model to investigate the role of oxidative stress in spermatogenesis.
Intraperitoneal administration of bacterial LPS (5mg/kg body weight) to adult male albino …