Innervation and serotoninergic receptors of the testis interact with local action of interleukin-1beta on steroidogenesis
I Gerendai, P Banczerowski, V Csernus… - Autonomic …, 2007 - Elsevier
Testosterone secretion by Leydig cells is affected by interleukin-1β (IL-1β). The aim of the
present study was to investigate whether partial denervation of the testis or local
administration of a serotonin (5-HT) receptor antagonist could alter the changes in testicular
steoidogenesis induced by IL-1β. Intratesticular administration of IL-1β was combined with
vasectomy or local injection of ketanserin (5-HT type 2 receptor antagonist) in immature
hemicastrated rats and the effect of the interventions on testicular steroidogenesis was …
present study was to investigate whether partial denervation of the testis or local
administration of a serotonin (5-HT) receptor antagonist could alter the changes in testicular
steoidogenesis induced by IL-1β. Intratesticular administration of IL-1β was combined with
vasectomy or local injection of ketanserin (5-HT type 2 receptor antagonist) in immature
hemicastrated rats and the effect of the interventions on testicular steroidogenesis was …
