Insulin-induced hypoglycemia, L-dopa and arginine stimulate GH secretion through different mechanisms in man
A Masuda, T Shibasaki, M Hotta, N Yamauchi, N Ling… - Regulatory peptides, 1990 - Elsevier
We sought to clarify the mechanisms of growth hormone (GH) secretion induced by insulin
hypoglycemia, l-dopa, and arginine in man. The secretion of GH as measured by increased
plasma level, in response to oral administration of 500 mg l-dopa or 30 min-infusion of
arginine, was not modified by prior intravenous administration of 200 μg GH-releasing
hormone (GHRH). It was, however, completely blocked by preadmininstered 50 μg SMS201-
995, a long-acting somatostatin (SRIH) analog. GH release with 200 μg GHRH was …
hypoglycemia, l-dopa, and arginine in man. The secretion of GH as measured by increased
plasma level, in response to oral administration of 500 mg l-dopa or 30 min-infusion of
arginine, was not modified by prior intravenous administration of 200 μg GH-releasing
hormone (GHRH). It was, however, completely blocked by preadmininstered 50 μg SMS201-
995, a long-acting somatostatin (SRIH) analog. GH release with 200 μg GHRH was …