[HTML][HTML] Allogeneic human mesenchymal stem cells restore epithelial protein permeability in cultured human alveolar type II Cells by SECRETION OF ANGIOPOIETIN …

X Fang, AP Neyrinck, MA Matthay, JW Lee - Journal of Biological Chemistry, 2010 - ASBMB
Acute lung injury is characterized by injury to the lung epithelium that leads to impaired
resolution of pulmonary edema and also facilitates accumulation of protein-rich edema fluid
and inflammatory cells in the distal airspaces of the lung. Recent in vivo and in vitro studies
suggest that mesenchymal stem cells (MSC) may have therapeutic value for the treatment of
acute lung injury. Here we tested the ability of human allogeneic mesenchymal stem cells to
restore epithelial permeability to protein across primary cultures of polarized human alveolar …