LncRNAs in vascular biology and disease

V Simion, S Haemmig, MW Feinberg - Vascular pharmacology, 2019 - Elsevier
Accumulating studies indicate that long non-coding RNAs (lncRNAs) play important roles in
the regulation of diverse biological processes involved in homeostatic control of the vessel
wall in health and disease. However, our knowledge of the mechanisms by which lncRNAs
control gene expression and cell signaling pathways is still nascent. Furthermore, only a
handful of lncRNAs has been functionally evaluated in response to pathophysiological
stimuli or in vascular disease states. For example, lncRNAs may regulate endothelial …