[HTML][HTML] Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice
MA Conti, S Even-Ram, C Liu, KM Yamada… - Journal of Biological …, 2004 - ASBMB
Previous work has shown that ablation or mutation of nonmuscle myosin heavy chain II-B
(NMHC II-B) in mice results in defects in the heart and brain with death occurring between
embryonic day 14.5 (E14. 5) and birth (Tullio, AN, Accili, D., Ferrans, VJ, Yu, ZX, Takeda, K.,
Grinberg, A., Westphal, H., Preston, YA, and Adelstein, RS (1997) Proc. Natl. Acad. Sci. USA
94, 12407–12412). Here we show that mice ablated for NMHC II-A fail to develop a normal
patterned embryo with a polarized visceral endoderm by E6. 5 and die by E7. 5. Moreover, A …
(NMHC II-B) in mice results in defects in the heart and brain with death occurring between
embryonic day 14.5 (E14. 5) and birth (Tullio, AN, Accili, D., Ferrans, VJ, Yu, ZX, Takeda, K.,
Grinberg, A., Westphal, H., Preston, YA, and Adelstein, RS (1997) Proc. Natl. Acad. Sci. USA
94, 12407–12412). Here we show that mice ablated for NMHC II-A fail to develop a normal
patterned embryo with a polarized visceral endoderm by E6. 5 and die by E7. 5. Moreover, A …