The use of NMR spectroscopy for the understanding of disease
GK Radda - Science, 1986 - science.org
GK Radda
Science, 1986•science.orgNuclear magnetic resonance spectroscopy can now be used to investigate the biochemical
energetics of human tissues and organs noninvasively. The method already has increased
our understanding of some muscle diseases, has provided information from muscle
metabolism about whole-body functions, control, and hormonal status, has helped in the
elucidation of hitherto unrecognized causes of disease, and yielded new ideas about the
control of bioenergetics in vivo. Studies on the biochemistry of human brain, liver, heart, and …
energetics of human tissues and organs noninvasively. The method already has increased
our understanding of some muscle diseases, has provided information from muscle
metabolism about whole-body functions, control, and hormonal status, has helped in the
elucidation of hitherto unrecognized causes of disease, and yielded new ideas about the
control of bioenergetics in vivo. Studies on the biochemistry of human brain, liver, heart, and …
Nuclear magnetic resonance spectroscopy can now be used to investigate the biochemical energetics of human tissues and organs noninvasively. The method already has increased our understanding of some muscle diseases, has provided information from muscle metabolism about whole-body functions, control, and hormonal status, has helped in the elucidation of hitherto unrecognized causes of disease, and yielded new ideas about the control of bioenergetics in vivo. Studies on the biochemistry of human brain, liver, heart, and kidney are just beginning. Further investigations of well-selected patients are likely to bring biochemistry and clinical practice closer together.
AAAS