Chemokines are a superfamily of small, secreted proteins that regulate cell traffic in
homeostatic and inflammatory conditions. Keratinocytes synthesize many chemokines,
including members of the CC and CXC subfamilies, such as regulated on activation of
normal T-cell expressed and secreted, gamma-interferon inducible protein-10, monokine
induced by gamma-interferon, and thymus-and activation-regulated chemokine. They also
express some chemokine receptors that mediate the inflammatory or immune response by …