[HTML][HTML] Neuropsychiatric comorbidities in adults with phenylketonuria: a retrospective cohort study

DA Bilder, JA Kobori, JL Cohen-Pfeffer… - Molecular genetics and …, 2017 - Elsevier
Adults with phenylketonuria (PKU) may experience neurologic and psychiatric disorders,
including intellectual disability, anxiety, depression, and neurocognitive dysfunction.
Identifying the prevalence and prevalence ratios of these conditions will inform clinical
treatment. This nested, case-controlled study used International Classification of Diseases,
Ninth Revision (ICD-9) codes from the MarketScan® insurance claims databases from 2006
to 2012 and healthcare claims data for US-based employer and government-sponsored …