Expression of the IL-23/Th17 pathway in lesions of hidradenitis suppurativa
C Schlapbach, T Hänni, N Yawalkar… - Journal of the American …, 2011 - Elsevier
BACKGROUND: Hidradenitis suppurativa is a debilitating chronic disease primarily affecting
intertriginous skin of the axillae, perineum, and inframammary regions. The pathogenesis of
this inflammatory disease is still poorly understood. Recently, increased attention has been
paid to the role of the immune system. OBJECTIVE: Since the interleukin 12 (IL-12)/T helper
1 (Th1) and the IL-23/Th17 pathways are believed to be crucially involved in the
pathogenesis of multiple chronic inflammatory diseases, we investigated the expression and …
intertriginous skin of the axillae, perineum, and inframammary regions. The pathogenesis of
this inflammatory disease is still poorly understood. Recently, increased attention has been
paid to the role of the immune system. OBJECTIVE: Since the interleukin 12 (IL-12)/T helper
1 (Th1) and the IL-23/Th17 pathways are believed to be crucially involved in the
pathogenesis of multiple chronic inflammatory diseases, we investigated the expression and …