[HTML][HTML] Effect of pyridostigmine on in vivo and in vitro respiratory muscle of mdx mice
GCS Amancio, A Grabe-Guimarães, D Haikel… - Respiratory Physiology …, 2017 - Elsevier
The current work was conducted to verify the contribution of neuromuscular transmission
defects at the neuromuscular junction to Duchenne Muscular Dystrophy disease
progression and respiratory dysfunction. We tested pyridostigmine and pyridostigmine
encapsulated in liposomes (liposomal PYR), an acetylcholinesterase inhibitor to improve
muscular contraction on respiratory muscle function in mdx mice at different ages. We
evaluated in vivo with the whole-body plethysmography, the ventilatory response to …
defects at the neuromuscular junction to Duchenne Muscular Dystrophy disease
progression and respiratory dysfunction. We tested pyridostigmine and pyridostigmine
encapsulated in liposomes (liposomal PYR), an acetylcholinesterase inhibitor to improve
muscular contraction on respiratory muscle function in mdx mice at different ages. We
evaluated in vivo with the whole-body plethysmography, the ventilatory response to …