The effect of telephone-administered cognitive–behavioral therapy on quality of life among patients with multiple sclerosis
D Cosio, L Jin, J Siddique… - Annals of Behavioral …, 2011 - academic.oup.com
D Cosio, L Jin, J Siddique, DC Mohr
Annals of Behavioral Medicine, 2011•academic.oup.comBackground Past research has found that a variety of physical, psychological, and social
factors can affect quality of life (QOL). These previous findings suggest that interventions that
address these factors could potentially improve QOL. Purpose The purpose of this study was
to examine whether cognitive behavioral therapy (CBT) can improve QOL, and if so, explore
which factors might mediate this effect. Methods This is a secondary analysis of a
randomized controlled trial. One hundred twenty-seven participants with multiple sclerosis …
factors can affect quality of life (QOL). These previous findings suggest that interventions that
address these factors could potentially improve QOL. Purpose The purpose of this study was
to examine whether cognitive behavioral therapy (CBT) can improve QOL, and if so, explore
which factors might mediate this effect. Methods This is a secondary analysis of a
randomized controlled trial. One hundred twenty-seven participants with multiple sclerosis …
Background
Past research has found that a variety of physical, psychological, and social factors can affect quality of life (QOL). These previous findings suggest that interventions that address these factors could potentially improve QOL.
Purpose
The purpose of this study was to examine whether cognitive behavioral therapy (CBT) can improve QOL, and if so, explore which factors might mediate this effect.
Methods
This is a secondary analysis of a randomized controlled trial. One hundred twenty-seven participants with multiple sclerosis and depression were randomly assigned to either a telephone-administered CBT (T-CBT) or telephone-administered supportive emotion-focused therapy (T-SEFT) intervention.
Results
Patients assigned to T-CBT showed significantly greater improvements in QOL compared with those assigned to T-SEFT. The greater improvement in QOL among T-CBT recipients was mediated by improvements in depression and positive affect. There was also inconsistent support for the superior effect of CBT on QOL being mediated by improvement in fatigue.
Conclusions
T-CBT provided greater QOL benefits compared with T-SEFT, which controlled for non-specific treatment components. This study further suggests that T-CBT procedures specific to the management of depression and positive affect were uniquely useful in improving QOL.
Oxford University Press