Early recovery following new onset anosmia during the COVID-19 pandemic–an observational cohort study

C Hopkins, P Surda, E Whitehead… - … -Head & Neck Surgery, 2020 - journals.sagepub.com
C Hopkins, P Surda, E Whitehead, BN Kumar
Journal of Otolaryngology-Head & Neck Surgery, 2020journals.sagepub.com
Background A rapidly evolving evidence suggests that smell and taste disturbance are
common symptoms in COVID-19 infection. As yet there are no reports on duration and
recovery rates. We set out to characterise patients reporting new onset smell and taste
disturbance during the COVID-19 pandemic and report on early recovery rates. Methods
Online Survey of patients reporting self-diagnosed new onset smell and taste disturbance
during the COVID-19 pandemic, with 1 week follow-up. Results Three hundred eighty-two …
Background
A rapidly evolving evidence suggests that smell and taste disturbance are common symptoms in COVID-19 infection. As yet there are no reports on duration and recovery rates. We set out to characterise patients reporting new onset smell and taste disturbance during the COVID-19 pandemic and report on early recovery rates.
Methods
Online Survey of patients reporting self-diagnosed new onset smell and taste disturbance during the COVID-19 pandemic, with 1 week follow-up.
Results
Three hundred eighty-two patents completed bot an initial and follow-up survey. 86.4% reported complete anosmia and a further 11.5% a very severe loss of smell at the time of completing the first survey. At follow-up 1 week later, there is already significant improvement in self-rating of severity of olfactory loss. 80.1% report lower severity scores at follow-up, 17.6% are unchanged and 1.9% are worse. 11.5% already report compete resolution at follow up, while 17.3% report persistent complete loss of smell, with reported duration being 1 to over 4 weeks. This is reflected in the overall cumulative improvement rate of 79% patients overall in the interval between surveys.
Conclusions
A review of the growing evidence base supports the likelihood that out cohort have suffered olfactory loss as part of COVID-19 infection. While early recovery rates are encouraging, long term rates will need to be further investigated and there may be an increase in patients with persistent post-viral loss as a result of the pandemic.
We further call for loss of sense of smell to be formerly recognised as a marker of COVID-19 infection.
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