The variable plasma quercetin response to 12-week quercetin supplementation in humans

F Jin, DC Nieman, RA Shanely, AM Knab… - European journal of …, 2010 - nature.com
F Jin, DC Nieman, RA Shanely, AM Knab, MD Austin, W Sha
European journal of clinical nutrition, 2010nature.com
Results: Quercetin supplementation over 12 weeks caused a significant increase in
overnight-fasted plasma quercetin, with a net increase of 332±21.0 and 516±30.8 μg/l for Q-
500 and Q-1000 compared with 53.6±6.4 μg/l for placebo (interaction effect, P< 0.001). The
increase in plasma quercetin was highly variable within each quercetin supplementation
group, but was unrelated to age, gender, BMI, fitness levels, or diet intake. Conclusions: In
summary, quercetin supplementation in doses of 500 and 1000 mg/day caused large but …
Results:
Quercetin supplementation over 12 weeks caused a significant increase in overnight-fasted plasma quercetin, with a net increase of 332±21.0 and 516±30.8 μg/l for Q-500 and Q-1000 compared with 53.6±6.4 μg/l for placebo (interaction effect, P< 0.001). The increase in plasma quercetin was highly variable within each quercetin supplementation group, but was unrelated to age, gender, BMI, fitness levels, or diet intake.
Conclusions:
In summary, quercetin supplementation in doses of 500 and 1000 mg/day caused large but highly variable increases in plasma quercetin that were unrelated to demographic or lifestyle factors.
nature.com