Calibrated automated thrombography demonstrates hypercoagulability in patients with idiopathic pulmonary arterial hypertension
A Tournier, D Wahl, A Chaouat, JP Max, V Regnault… - Thrombosis research, 2010 - Elsevier
INTRODUCTION: Pathogenesis of idiopathic pulmonary arterial hypertension (iPAH)
includes endothelial dysfunction and in situ thrombosis. A hypercoagulable state has also
been postulated but never demonstrated. Our objective was to determine whether patients
with iPAH had a hypercoagulable state using calibrated automated thrombography (CAT), a
new tool to phenotype coagulation in vitro. PATIENTS AND METHODS: 16 patients with
iPAH and 29 controls were studied. In vitro platelet dependent coagulation phenotyping by …
includes endothelial dysfunction and in situ thrombosis. A hypercoagulable state has also
been postulated but never demonstrated. Our objective was to determine whether patients
with iPAH had a hypercoagulable state using calibrated automated thrombography (CAT), a
new tool to phenotype coagulation in vitro. PATIENTS AND METHODS: 16 patients with
iPAH and 29 controls were studied. In vitro platelet dependent coagulation phenotyping by …