Orbitofrontal volume reductions during emotion recognition in patients with major depression

J Scheuerecker, EM Meisenzahl, N Koutsouleris… - Journal of Psychiatry and …, 2010 - jpn.ca
Background: Major depressive disorder is associated with both structural and functional
alterations in the emotion regulation network of the central nervous system. The relation
between structural and functional changes is largely unknown. Therefore, we sought to
determine the relation between structural differences and functional alterations during the
recognition of emotional facial expressions. Methods: We examined 13 medication-free
patients with major depression and 15 healthy controls by use of structural T 1-weighted …