Inhibitory effects of electrically evoked activation of ventrolateral orbital cortex on the tail-flick reflex are mediated by periaqueductal gray in rats
YQ Zhang, JS Tang, B Yuan, H Jia - Pain, 1997 - Elsevier
The present study found in lightly anesthetized rats that the radiant heat-evoked tail flick (TF)
reflex was markedly inhibited by a unilateral electrical stimulation (a 20 ms train of 0.2 ms,
100 Hz, 30–100 μA pulses) of the ventrolateral orbital cortex (VLO), with the tail flick latency
(TFL) being increased. The mean threshold of VLO stimulation for producing inhibition of the
TF reflex was 39.2±8.7 μA (n= 26), and this inhibitory effect increased following increasing
stimulation intensity from 40 to 70 μA. The inhibition developed and remained during the …
reflex was markedly inhibited by a unilateral electrical stimulation (a 20 ms train of 0.2 ms,
100 Hz, 30–100 μA pulses) of the ventrolateral orbital cortex (VLO), with the tail flick latency
(TFL) being increased. The mean threshold of VLO stimulation for producing inhibition of the
TF reflex was 39.2±8.7 μA (n= 26), and this inhibitory effect increased following increasing
stimulation intensity from 40 to 70 μA. The inhibition developed and remained during the …