A high-powered view of the filtration barrier

J Peti-Peterdi, A Sipos - Journal of the American Society of …, 2010 - journals.lww.com
Multiphoton excitation fluorescence microscopy is a powerful noninvasive imaging
technique for the deep optical sectioning of living tissues. Its application in several intact
tissues is a significant advance in our understanding of organ function, including renal
pathophysiological mechanisms. The glomerulus, the filtering unit in the kidney, is one good
example of a relatively inaccessible and complex structure, with cell types that are otherwise
difficult to study at high resolution in their native environment. In this article, we address the …