[HTML][HTML] New MCM8 mutation associated with premature ovarian insufficiency and chromosomal instability in a highly consanguineous Tunisian family
N Bouali, B Francou, J Bouligand, D Imanci… - Fertility and …, 2017 - Elsevier
Objective To identify the gene (s) involved in the etiology of premature ovarian insufficiency
in a highly consanguineous Tunisian family. Design Genetic analysis of a large
consanguineous family with several affected siblings. Setting University hospital-based
cytogenetics and molecular genetics laboratories. Patient (s) A highly consanguineous
Tunisian family with several affected siblings born to healthy second-degree cousins.
Intervention (s) None. Main Outcome Measure (s) Targeted exome sequencing was …
in a highly consanguineous Tunisian family. Design Genetic analysis of a large
consanguineous family with several affected siblings. Setting University hospital-based
cytogenetics and molecular genetics laboratories. Patient (s) A highly consanguineous
Tunisian family with several affected siblings born to healthy second-degree cousins.
Intervention (s) None. Main Outcome Measure (s) Targeted exome sequencing was …