Cardiac actions of protein kinase C isoforms
SF Steinberg - Physiology, 2012 - journals.physiology.org
Physiology, 2012•journals.physiology.org
Protein kinase C (PKC) isoforms have emerged as important regulators of cardiac
contraction, hypertrophy, and signaling pathways that influence ischemic/reperfusion injury.
This review focuses on newer concepts regarding PKC isoform-specific activation
mechanisms and actions that have implications for the development of PKC-targeted
therapeutics.
contraction, hypertrophy, and signaling pathways that influence ischemic/reperfusion injury.
This review focuses on newer concepts regarding PKC isoform-specific activation
mechanisms and actions that have implications for the development of PKC-targeted
therapeutics.
Protein kinase C (PKC) isoforms have emerged as important regulators of cardiac contraction, hypertrophy, and signaling pathways that influence ischemic/reperfusion injury. This review focuses on newer concepts regarding PKC isoform-specific activation mechanisms and actions that have implications for the development of PKC-targeted therapeutics.
American Physiological Society