Organ-specific differences in achieving tolerance
MLL Madariaga, D Kreisel… - Current opinion in organ …, 2015 - journals.lww.com
MLL Madariaga, D Kreisel, JC Madsen
Current opinion in organ transplantation, 2015•journals.lww.comTolerance induction protocols that are successful in patients transplanted with 'tolerance-
prone'organs such as kidneys and livers will most likely not succeed in recipients of
'tolerance-resistant'organs such as hearts and lungs. Separate clinical trials using more
robust tolerance protocols will be required to achieve tolerance in heart and lung recipients.
prone'organs such as kidneys and livers will most likely not succeed in recipients of
'tolerance-resistant'organs such as hearts and lungs. Separate clinical trials using more
robust tolerance protocols will be required to achieve tolerance in heart and lung recipients.
Summary
Tolerance induction protocols that are successful in patients transplanted with ‘tolerance-prone’organs such as kidneys and livers will most likely not succeed in recipients of ‘tolerance-resistant’organs such as hearts and lungs. Separate clinical trials using more robust tolerance protocols will be required to achieve tolerance in heart and lung recipients.
Lippincott Williams & Wilkins