Combined antibody and DNA detection for early diagnosis of leptospirosis after a disaster
H Iwasaki, H Chagan-Yasutan, PSA Leano… - … and Infectious Disease, 2016 - Elsevier
Early diagnosis based on laboratory confirmation is essential for managing leptospirosis.
This study investigated the effectiveness of a novel method of detecting leptospirosis that
combines measurement of anti-Leptospira antibodies by the microscopic agglutination test
(MAT), enzyme-linked immunosorbent assay (ELISA), and immunochromatographic test
(ICT) and leptospiral DNA by loop-mediated isothermal amplification (LAMP) and real-time
PCR in plasma and 2 types of urine pellets. Of 113 suspected cases, 68.1%, 76.1%, and …
This study investigated the effectiveness of a novel method of detecting leptospirosis that
combines measurement of anti-Leptospira antibodies by the microscopic agglutination test
(MAT), enzyme-linked immunosorbent assay (ELISA), and immunochromatographic test
(ICT) and leptospiral DNA by loop-mediated isothermal amplification (LAMP) and real-time
PCR in plasma and 2 types of urine pellets. Of 113 suspected cases, 68.1%, 76.1%, and …
