Prognosis of grade 3–4 acute GVHD continues to be dismal
K Jamani, JA Russell, A Daly, D Stewart… - Bone marrow …, 2013 - nature.com
K Jamani, JA Russell, A Daly, D Stewart, L Savoie, P Duggan, J Storek
Bone marrow transplantation, 2013•nature.comSurvival after hematopoietic cell transplant (HCT) has improved since 2000. 1 However, it is
unclear whether improvement in survival after grade 3–4 acute GVHD (aGVHD) has
paralleled the improvement in survival after HCT. This would be expected, as new
immunosuppressive drugs and antimicrobial treatment, and prophylaxis options have
become available since 2000. We set out to determine the long-term survival of patients with
grade 3–4 aGVHD at our institution after 2000, as well as to review the literature to identify …
unclear whether improvement in survival after grade 3–4 acute GVHD (aGVHD) has
paralleled the improvement in survival after HCT. This would be expected, as new
immunosuppressive drugs and antimicrobial treatment, and prophylaxis options have
become available since 2000. We set out to determine the long-term survival of patients with
grade 3–4 aGVHD at our institution after 2000, as well as to review the literature to identify …
Survival after hematopoietic cell transplant (HCT) has improved since 2000. 1 However, it is unclear whether improvement in survival after grade 3–4 acute GVHD (aGVHD) has paralleled the improvement in survival after HCT. This would be expected, as new immunosuppressive drugs and antimicrobial treatment, and prophylaxis options have become available since 2000. We set out to determine the long-term survival of patients with grade 3–4 aGVHD at our institution after 2000, as well as to review the literature to identify survival of this patient population before and after 2000.
nature.com