Decidual CD4+ CD25+ CD127dim/− regulatory T cells in patients with unexplained recurrent spontaneous miscarriage
SH Bao, XP Wang, Q De Lin, WJ Wang, GJ Yin… - European Journal of …, 2011 - Elsevier
OBJECTIVES: To investigate the frequency and function of CD4+ CD25+ CD127dim/−
regulatory T (Treg) cells in decidua of patients with unexplained recurrent spontaneous
miscarriage (URSM). STUDY DESIGN: The decidual lymphocytes from patients who
experienced URSM and normal pregnant women (controls) were collected by Ficoll density
gradient centrifugation. CD4+ CD25+ CD127dim/− Treg cells were isolated by magnetic cell
sorting. The proportion of Treg cells and IL-10, TGF-β in Treg cells were determined by flow …
regulatory T (Treg) cells in decidua of patients with unexplained recurrent spontaneous
miscarriage (URSM). STUDY DESIGN: The decidual lymphocytes from patients who
experienced URSM and normal pregnant women (controls) were collected by Ficoll density
gradient centrifugation. CD4+ CD25+ CD127dim/− Treg cells were isolated by magnetic cell
sorting. The proportion of Treg cells and IL-10, TGF-β in Treg cells were determined by flow …