Bile acid levels are increased in the liver of patients with steatohepatitis
MM Aranha, H Cortez-Pinto, A Costa… - European journal of …, 2008 - journals.lww.com
Background/aims The pathogenesis of steatohepatitis remains largely unknown; however,
bile acids may play a role as potential mediators of liver damage. The aim of this study was
to characterize bile acid profiles in liver tissue of patients with steatohepatitis. Methods Bile
acid composition was determined by gas–liquid chromatography in liver tissue from patients
with nonalcoholic steatohepatitis (NASH; n= 15), patients with alcoholic steatohepatitis
(ASH; n= 14), and controls (n= 8). Liver biopsies were graded for steatosis, inflammation …
bile acids may play a role as potential mediators of liver damage. The aim of this study was
to characterize bile acid profiles in liver tissue of patients with steatohepatitis. Methods Bile
acid composition was determined by gas–liquid chromatography in liver tissue from patients
with nonalcoholic steatohepatitis (NASH; n= 15), patients with alcoholic steatohepatitis
(ASH; n= 14), and controls (n= 8). Liver biopsies were graded for steatosis, inflammation …