Which multicenter randomized controlled trials in critical care medicine have shown reduced mortality? A systematic review
CA Santacruz, AJ Pereira, E Celis… - Critical care …, 2019 - journals.lww.com
Objectives: To determine which multicenter randomized controlled trials in critically ill
patients have shown that the study intervention was associated with a statistically significant
reduction in mortality. Our analysis provides an update to a report published 10 years ago.
Data Sources: MEDLINE database and PubMed interface from inception until April 30, 2019.
Study Selection: All adult multicenter randomized controlled trials that evaluated the effects
of any intervention or monitoring system in critically ill patients and reported mortality as a …
patients have shown that the study intervention was associated with a statistically significant
reduction in mortality. Our analysis provides an update to a report published 10 years ago.
Data Sources: MEDLINE database and PubMed interface from inception until April 30, 2019.
Study Selection: All adult multicenter randomized controlled trials that evaluated the effects
of any intervention or monitoring system in critically ill patients and reported mortality as a …